Disclaimer
What the evidence on this site does and does not mean. Last updated 26 August 2026.
Not evaluated by the FDA
These statements have not been evaluated by the Food and Drug Administration. Any product described on this site is not intended to diagnose, treat, cure, or prevent any disease. Dietary supplements are not drugs and are not reviewed or approved by the FDA before they are sold.
Not medical advice
Nothing on this site is medical advice, diagnosis, or treatment, and reading it does not create a clinician relationship. Talk to a physician or another qualified professional about your knees, your medications, and your history before you change anything. If you think you have a medical emergency, call your doctor or emergency services.
Who should not use a supplement like this
Do not use if you are pregnant or nursing. Talk to your physician first if you take medication — particularly blood thinners, anti-inflammatories, or diabetes medication — or if you have a bleeding disorder, gallbladder disease, liver disease, or an upcoming surgery. Not intended for anyone under 18. Stop use and consult a physician if you have an adverse reaction.
The studies we cite are not studies of our product
Every trial referenced on this site tested an individual ingredient or branded extract, in a specific population, at a specific dose, for a specific length of time. None of them tested a True Metric Labs product. We cite them to show where our doses come from, not to claim their results as ours. Where a study was funded by or linked to an ingredient supplier, we say so on the page.
Percentages and outcomes
Where we quote a number, we quote it the way the paper reported it, including whether the change was measured within a treatment group or against placebo. A within-group change is not the same as a placebo-controlled effect, and we will not present one as the other. Trial averages do not predict what happens to any individual, and we do not promise a timeline.
Individual results vary
Joint pain has many causes and many confounders. Age, weight, activity, prior injury, arthritis stage, and other medications all affect what an ingredient does. Some people in these trials improved, some did not, and some received placebo and improved anyway.
No product is for sale
There is no checkout on this site and no product is currently offered for sale. Formulas, doses, and pricing described here are subject to change or removal before anything ships, including if the underlying evidence stops holding up.
Third-party links and names
Branded ingredient names, journals, and researchers are referenced for identification only. Their use does not imply endorsement of True Metric Labs by those parties, and we are not responsible for the content of any external site we link to.
Accuracy and changes
We try to describe the evidence accurately and to correct errors when we find them. We may update, amend, or withdraw anything on this site at any time. If you believe we have described a study incorrectly, tell us and we will fix it or take it down.